Senior Scientist II, Chemistry (Drug Conjugates)

Company Description

About AbbVie

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience - and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at . Follow @abbvie on LinkedIn, Facebook , Instagram , X and YouTube.

Job Description

We are looking for a highly motivated person who can make scientific contributions across synthetic molecule modalities, with a focus on driving the development of drug-conjugate programs from FIH to late-stage development. The candidate will lead in the development of conjugation chemistry as well as downstream unit operations culminating in drug substance and may have supervisory responsibilities. The candidate will serve as the chemistry representative on the Drug Substance team for drug-conjugate development programs and would be responsible for developing timelines and executing activities required for drug substance. Working with analytical and manufacturing colleagues, the candidate will develop productive collaborations and communications with scientific teams. 

Responsibilities: 

• The candidate will lead activities associated with process development and characterization for new drug conjugates. 

• Develop and characterize drug-conjugate (and other modalities) processes in the laboratory and translate them to scalable processes. 

• The candidate will utilize his/her expertise to generate internal collaborations as necessary to further program goals.

• Author and review key regulatory documents, laboratory data, technical memos and reports. 

• The position involves multi-disciplinary interactions with organic chemists, analytical chemists, engineers, drug product development, and program management. The selected candidate will collaborate with cross-functional CMC teams to advance pre-clinical and clinical candidates.

• The candidate will encourage ideas for continuous improvement activities and initiatives within work group. 

• The candidate will understand and adhere to corporate standards regarding code of conduct, safety and GXP compliance.  

Qualifications

• BS (12+ years); MS (10+ years) or PhD (4+ years) in Chemistry or allied field, with 2+ years of previous work experience in a pharmaceutical laboratory setting. 

• Experience in drug-conjugate process development.

• Proven scientific leadership; strong interpersonal and communication skills for facilitating collaborations and a demonstrated ability to lead cross-functional process development teams. 

• The successful candidate will have a strong understanding of modern organic chemistry, mechanistic theory, control strategy development, and regulatory starting material strategies. 

Key AbbVie Competencies: 

Interacts well with diverse groups within function and maintain strong working relationships with internal and external collaborators to enable higher performance.  

• Learns fast, grasps the "essence" and can change course quickly where indicated. 

• Raises the bar and is never satisfied with the status quo. 

• Creates a learning environment, open to suggestions and experimentation for improvement. 

• Embraces the ideas of others, nurtures innovation and manages innovation to reality. 

Additional Information

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law: ​

• The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location, and we may ultimately pay more or less than the posted range. This range may be modified in the future. ​

• We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.​

• This job is eligible to participate in our long-term incentive programs. ​

Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole and absolute discretion unless and until paid and may be modified at the Company’s sole and absolute discretion, consistent with applicable law.​

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community.  Equal Opportunity Employer/Veterans/Disabled. 

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